John opens his letter by addressing the seven churches in Asia, a region that was significant in early Christianity. He extends a greeting of grace and peace, which is a common apostolic salutation, emphasizing the divine favor and tranquility that believers receive from God. The description of God as "him who is, and who was, and who is to come" highlights His eternal nature, underscoring that God transcends time and is always present with His people. This eternal aspect assures believers of God's unchanging nature and His sovereignty over all of history.
The reference to the "seven spirits before his throne" is often interpreted as a symbolic representation of the Holy Spirit in His fullness and perfection. The number seven in biblical literature frequently signifies completeness or perfection, suggesting the complete and perfect work of the Holy Spirit in the world and within the church. This greeting not only sets a spiritual tone for the messages to the churches but also reassures them of the divine presence and guidance they have through the Holy Spirit, encouraging them to remain steadfast in their faith.